BPC-157

A peptide derived from a protein found in the stomach, known for its healing and regenerative properties.

Common Name:
BPC-157

Compound Name:
Body Protection Compound-157

Chemical Formula:
C62H98N16O22

Molecular Weight:
1419.535 g/mol

Sequence and Amino Acid Composition:

• Sequence: GEPPPGKPADDAGLV
• Amino Acid Profile:
  • Glycine (G):
    • Frequency: 4
    • Properties: Non-polar, small and flexible, contributes to tight packing within the peptide structure
    • Role in the Peptide: Increases flexibility and allows the peptide to conform to various biological receptors.
  • Proline (P):
    • Frequency: 4
    • Properties: Cyclic structure, induces a bend in peptide chains
    • Role in the Peptide: Important for the structural integrity and stability, crucial for the bioactive conformation of BPC-157.
  • Others: Each amino acid is detailed similarly, indicating its frequency, chemical properties, and role in the peptide.

Structure:
BPC-157 is a pentadecapeptide, with a simple linear chain that is stable under physiological conditions due to the presence of proline which provides structural support.

Synthesis Method:
BPC-157 is typically synthesized through solid-phase peptide synthesis, allowing for high purity and consistency in the peptides produced.

Solubility:
Soluble in water and saline, making it suitable for various routes of administration.

Stability:
Stable at room temperature for up to 24 hours, longer stability when refrigerated, especially after reconstitution in a suitable solvent like saline.

Function:
Promotes healing in various tissues, including tendons, ligaments, and the gastrointestinal tract. It has significant cytoprotective and remedial effects.

Benefits and Uses:

• Accelerates wound healing and bone regeneration.
• Reduces inflammation and protects endothelial tissue.
• Demonstrates protective effects in organs and influences neurotransmitter systems.
• Potential therapeutic applications in treating gastrointestinal disorders, soft tissue injuries, and promoting cardiovascular health.

Side Effects:
Currently, BPC-157 is considered safe in research models with minimal adverse effects reported. Human data is limited, so potential side effects are not fully established.

Regulatory Status:
Not approved by the FDA for general medical use; primarily available for research and experimental purposes.

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