Noopept

A synthetic peptide that is reported to have cognitive-enhancing and neuroprotective effects. It is studied for its potential to improve learning, memory, and protect against neurotoxicity.

Common Name:
Noopept

Compound Name:
N-Phenylacetyl-L-prolylglycine ethyl ester

Chemical Formula:
C17H22N2O4

Molecular Weight:
318.37 g/mol

Sequence and Amino Acid Composition:

  • Not applicable: Noopept is not a peptide but a dipeptide mimetic, meaning it is designed to mimic the action of a peptide while being structurally different.

Structure:
Noopept is a synthetic molecule that resembles the dipeptide structure. It is a small, psychotropic compound which has been enhanced to cross the blood-brain barrier more effectively than its predecessors.

Synthesis Method:
Synthesized chemically as a dipeptide mimetic, ensuring high precision in molecular structure for enhanced cognitive effects.

Solubility:
Soluble in alcohol and partially soluble in water, which allows for various forms of administration including oral and sublingual.

Stability:
Stable under normal environmental conditions. It should be stored in a cool, dry place to maintain potency over time.

Function:
Noopept is primarily known for its neuroprotective properties. It increases the expression of NGF (nerve growth factor) and BDNF (brain-derived neurotrophic factor) in the hippocampus, enhancing cognitive functions such as memory, learning, and clarity of thought.

Benefits and Uses:

  • Widely used as a nootropic supplement for enhancing cognitive function, memory enhancement, and increasing focus and learning capability.
  • Investigated for potential therapeutic effects in the treatment of Alzheimer’s disease, other forms of dementia, and various cognitive impairments.
  • Some studies suggest potential anxiolytic and mild psychostimulatory effects, making it useful in treating mild cognitive disorders linked to anxiety.

Side Effects:
Noopept is generally well-tolerated with minimal side effects; however, some users report short-term side effects such as headaches, dizziness, and irritability, which typically occur due to high doses or initial usage.

Regulatory Status:
Noopept is available as a dietary supplement in the USA and as a prescription medication in some countries, including Russia, where it is used to treat various cognitive disorders.

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